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Document 2581
DOCN M94A2581
TI Trends in distribution of HIV infection by risk factors in French
Brittany 1990-1993.
DT 9412
AU Cartier F; Favre C; Michelet C; Arvieux C; Camus C; Ruffault A; Dept. of
Infect. Diseases, University Rennes, France.
SO Int Conf AIDS. 1994 Aug 7-12;10(1):271 (abstract no. PC0005). Unique
Identifier : AIDSLINE ICA10/94369994
AB Actions of prevention of HIV disease are based upon the distribution of
infected persons by risk category. Most of studies deal with new AIDS
patients, years after infection. An earlier assessment, at the time of
HIV serological detection is necessary. Such data have not been
extensively reported and time between infection and serological
detection was usually unknown. The aim of the study was to define trends
in distribution of HIV infection by risk factors through the analysis of
new seropositive patients, taking in account the previous duration of
infection. All the patients seen at our hospital less than 4 months
after ascertained new HIV seropositivity were prospectively studied:
risk factor, previous duration of infection according to: 1. anamnestic
findings and previous serological tests (infection < 6 months, > 2
years) 2. clinical stage 3. P24 Ag, 4. CD4 T cells. 134 patients in
1990-1991 (B) and 96 patients in 1992-1993 (C) were enrolled. Comparison
between the 2 groups and with 197 new AIDS patients reported in
1990-1993 in the same region (A) was made according to risk factors and
criteria of duration of infection (chi 2 and t tests). Ratio of
heterosexuality has increased 8.6% (A), 19.4% (B), 20.8% (C), B+C vs A:
p < 0.001, C vs A: p < 0.01. Ratio of IVDU was 22.8% (A), 17.9% (B),
14.6% (C): N.S., and that of blood products recipients (BPR) was 5.6%
(A), 4.3% (B), 3.1% (C): N.S. Together, these 2 last categories have
decreased: C vs A: p < 0.05. Previous duration of infection was longer
in C than B, according to criterion 4: CD4 T cells 395 vs 591: p < 0.01.
It was longer in all IVDU (B+C) than in all homosexuals (criteria 1 and
3), in all BPR than in all homosexuals (criterion 1), in all homosexuals
than in all heterosexuals (criterion 4). CONCLUSION--Heterosexuality
risk is relatively increasing. Longer previous duration of infection in
recent new seropositive patients suggests a decreasing incidence of HIV
transmission in our country, particularly in IVDU and homosexuals.
DE Blood Transfusion/ADVERSE EFFECTS France/EPIDEMIOLOGY Homosexuality
Human HIV Infections/*EPIDEMIOLOGY/TRANSMISSION HIV Seropositivity
Risk Factors Substance Abuse, Intravenous/COMPLICATIONS MEETING
ABSTRACT
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).